Single cell

RiboLace

7 March 2024

Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition

Mouse embryo gene activation relies on translational regulation, not just gene transcription. Researchers identified key maternal factors activated during specific stages that are crucial for embryo development, potentially impacting fertility research.

RiboLace

7 March 2024

Single-cell transcriptome and translatome dual-omics reveals potential mechanisms of human oocyte maturation

Dual-omics approach (T&T-seq) reveals distinct translational patterns in mouse & human oocytes, aiding oocyte maturation research. OOSP2 identified as key factor.

Single cell

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Single cell

RiboLace

Profiling and functional characterization of maternal mRNA translation during mouse maternal-to-zygotic transition

RiboLace

Single-cell transcriptome and translatome dual-omics reveals potential mechanisms of human oocyte maturation