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mRNA localization is key for cell migration. Boraas et al identify hundreds of FA-enriched mRNAs & reveal that G3BP1 RNPs regulate FA function. By enhancing FA protein mobility & size, G3BP1 promotes cell speed—unveiling a new role beyond stress response.
HIV-1 gene expression is tightly regulated at multiple levels. Using RiboLace & proteomics, Labaronne et al reveal how translation & post-translational mechanisms shape infection. Notably, how uORF-derived peptides elicit immune responses.
Ovarian endometriosis impacts oocyte quality, but the molecular mechanisms remain unclear. Using RiboLace pulldown, Diao et al reveal key translatomic and transcriptomic pathways—oxidative stress, meiosis, and spliceosome—linked to infertility
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